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Poliovirus Induces Apoptosis in the Mouse Central Nervous System

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Figure

FIG. 1. Detection of DNA ladders in spinal cords from PV-infected TgPVR(A) and nontransgenic Swiss (B) mice
FIG. 2. DNA fragmentation analysis by ELISA (A) and PV production (B) in homogenate supernatants of the forebrains, brain stems, and spinal cords of PV-1Mahoney-infected TgPVR mice
FIG. 3. Immunofluorescent codetection of apoptosis and viral antigens in spinal cords from PV-1-infected TgPVR and nontransgenic Swiss mice
FIG. 4. Cresyl violet staining of longitudinal section through the ventral horn of the spinal cord from a TgPVR mouse 4 days after infection with PV-1 Mahoney.Chromatolyzed (curved arrows) and nonchromatolyzed (thin arrows) neurons are indicated, as well a
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