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Cell Cycle Arrest by Human Cytomegalovirus 86-kDa IE2 Protein Resembles Premature Senescence

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Figure

FIG. 1—Continued.
FIG. 2. Differential SA-�culture conditions were infected with HCMV (MOI, 1) and stained for SA-mock-infected cells cultured in DMEM–10% FCS; column 2, mock-infected cells cultured in DMEM–0.2% FCS; column 3, HCMV-infected cellscultured in DMEM–10% FCS; co
FIG. 3. Effect of HCMV infection on cell cycle regulatory proteins.Immunoblots of cellular lysates corresponding to mock- and HCMV-
FIG. 4. Infection of senescent cells enhances HCMV replication. (A) HELF seeded at both low (2 �densities were serum starved for 72 h and then stained for SA-immunohistochemically stained for IE antigens with commercial anti-IEA Abs
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