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FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model

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Academic year: 2020

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Figure

Fig. 1 FTY720 suppresses viability of MM cells without significant effect on HM cells
Fig. 2 PP2A is inhibited in MM and FTY720 reactivates it. a Quantification of PP2A activity in indicated MM and HM cells was performed using a PP2A-specific enzymatic activity assay
Fig. 3 FTY720 induces programmed cell death in MM cells. were used as controls of loading and fractions’ purity
Fig. 4 FTY720 reduces tumor growth in MM syngeneic model without causing toxicity. a Suppression of viability of AB1 mouse cell line in vitro upon 48 h of treatment with indicated FTY720 doses

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