• No results found

The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

N/A
N/A
Protected

Academic year: 2020

Share "The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism"

Copied!
11
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Figure 1 Effect of eplerenone and PF-03882845 on urinary Na+/K+ in rats. Eplerenone (A) and PF-03882845 (B) elicited a dose-dependentincrease in urinary Na+/K+ ratio in Sprague-Dawley rats following administration of single doses
Figure 2 Effects of eplerenone on urinary log10 Na+/K+ in humans. Eplerenone elicited a dose-dependent increase in urinary Na+/K+ inhumans
Figure 4 Effect of chronic administration of eplerenone and PF-03882845 on plasma aldosteronerepresented as mean + SEM

References

Related documents

Twenty-five percent of our respondents listed unilateral hearing loss as an indication for BAHA im- plantation, and only 17% routinely offered this treatment to children with

In this paper, we propose a chosen message attack on ELSA, with which we can obtain valid signatures by repeatedly accessing a signing oracle. Recall that ELSA possesses

In order to determine the intracellular localisation of fluorescent-labelled conjugates, cell uptake experiments were performed in B16F10 and HepG2 cells and fixed

Therefore the aim of this observational study was to assess the utility of the MYMOP2 and W-BQ12 health outcomes measures for measuring clinical change asso- ciated with a course

Some heavy metals such as Fe, Mo and Mn are essential micronutrient for plants al low concentration, but in higher doses they may cause metabolic disorders and growth

• Haftungsrechtlich ist für die Anerkennung von Bedeutung, wenn gerichtlich oder außergerichtlich nach Einholung eines medizinischen Gutachtens ein Behandlungsfehler

The variables examined in this study were gender, medication-related variables (such as drug type, dose, frequency of administra- tion, route of administration, dosage

Wir führten bei 663 symptomatischen Patienten, die sich einer Bypass-Operation unterzogen hatten, im Schnitt nach 1.000 Tagen eine Kontrollangiographie durch, die für die