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The Cellular Protein Lyric Interacts with HIV-1 Gag

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TABLE 1. HIV-1 Gag interaction candidates identified in affinity purification screens
FIG. 1. Coimmunoprecipitation and virion incorporation of Lyric. (A) Lysates from 293T cells transfected with either pCHIVEGFP or pEGFPc1were subjected to immunoprecipitations using anti-GFP microbeads, followed by immunoblotting with anti-Lyric antibody
FIG. 2. Mapping of Lyric interaction domains in HIV-1 Gag. (A) Domain organization of HIV-1 Gag
FIG. 3. Importance of Gag NC domain for Lyric interaction. (A) Lysates of 293T cells transfected with pCHIVEGFPimmunoprecipitation with anti-GFP microbeads in the presence or absence of RNase (60immunoblotting with anti-Lyric antibody
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