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Role of Capsid Anchor in the Morphogenesis of Zika Virus

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Academic year: 2019

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Figure

FIG 1 (A) Schematic representation of the genomic organization of flavivirus structural proteins (upper panel) andthe membrane topology and cleavage sites for NS2B/NS3, furin and signal peptidase, indicated by red, blue,and black arrows, respectively (lower
FIG 2 Production of WNV, DENV2, and ZIKV pseudoviruses. (A) Cytofluorimetry profiles of Vero cells infected withpanels) of cell extracts and pellets of ultracentrifuged supernatants of HEK293T cells cotransfected with theWNV-rep and the indicated packaging c
FIG 3 Generation and characterization of Zika pseudoviruses. (A) Scheme and sequence at the C-Pr junction ofdifferent C-PrME ZIKV/WNV chimeras used as packaging constructs and numbered 1 to 6
FIG 4 Cleavage by NS2B/NS3 viral protease and signal peptidase. (A) Schematic representation of packaging construct carryingpeptide sec (gray) is also shown
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