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Inhibitory Effect of Individual or Combinations of Broadly Neutralizing Antibodies and Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission

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Figure

FIG 1 Neutralization assays. (A) Frozen CD4� cells were thawed, stimulated overnight with IL-2, and infected with one of the four GFP-labeled HIV-1 Envvariants to prepare cell-associated virus
FIG 2 Infection with cell-associated or cell-free WITOdifferent antibodies. TZM-bl (A and B) or A3R5 (C and D) target cells wereinfected with cell-associated (A and C) or cell-free (B and D) WITO virus in thepresence of different concentrations (20 to 0.00
TABLE 1 Comparison of cell-associated and cell-free virusneutralizationa
TABLE 2 Antibody and inhibitor relative IC50s by the TZM-bl and A3R5 assaysa
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