• No results found

Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope.

N/A
N/A
Info
Download
Protected

Academic year: 2019

Share "Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope."

Copied!
6
0
0

Loading.... (view fulltext now)

Download now ( 6 Page )

Full text

Loading

Figure

FIG. 1.recombinantofpp89uninfectedpanel),wereassayA5-merRatio,pp89 pp89 IEl epitope sequences are essential for the recognition of by BALB/c CTL
FIG. 2.openflanking(B)acidsepitopeproteins.andresidueschimericcaserestrictionsequences.sameIEl Schematic representation (A) and amino acid sequence of pp89 and chimeric proteins
TABLE 1. Adjustment to nonapeptide length by symmetricalanine flanking
FIG. 6.afterDL,MCMVatedtiterspp89proteins.nylonlymphocytes Antiviral effect of CD8+ T lymphocytes sensitized with IEl epitope sequences

References

Download now ( PDF - 6 Page - 1.26 MB )

Related documents

Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope.

Results of PBMCs (triplicates) from 8 acutely (acute), 8 postacutely (postacute), and 12 chronically (chronic) WHV-infected woodchucks and 8 WHV-negative animals (negative)

Genetic diversity of simian immunodeficiency viruses from West African green monkeys: evidence of multiple genotypes within populations from the same geographical locale.

In the case of SIVagm from the sabaeus subspecies, analysis of a complete provirus sequence (28) has revealed that some regions of the genome are more closely related to the

Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus.

The intermediate NF- k B-stimulating activity showed by de- rivatives of LMP that have truncated carboxy termini, such as LMP-C D 55 (Table 2), correlated with their intermediate

Analysis of deletions and thermosensitive mutations in Rous sarcoma virus gag protein p10.

Deletion mutant D14 showed a 20- to 30-fold decrease in the amount of virus released in the medium in comparison with the wild type, while D13, D23, D25, and D45 produced 30- to

Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component.

To examine the expression of the 17 gene product during vaccinia virus infection of cultured cells, BSC40 monolayers were infected synchronously with wild-type vaccinia virus

Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism.

In this study, we compared two groups of HIV isolates which differed in infectivity for 1022 cells and macrophages in order to examine which combinations of amino acid sequences in

Inactivated simian immunodeficiency virus vaccine failed to protect rhesus macaques from intravenous or genital mucosal infection but delayed disease in intravenously exposed animals.

exposed control animals that failed to seroconvert at 40 days following infection (Fig. Humoral immune responses as determined by immuno- blot. Lanes a and b show positive and

Marmoset lymphoblastoid cells as a sensitive host for isolation of measles virus.

B95-8, an Epstein-Barr virus-transformed marmoset B-lymphoblastoid cell line, and its derivative B95a, capable of attachment to a substrate surface, were 10,000-fold more sensitive