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Biological Significance of Local TGF-β Activation in Liver Diseases

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Figure

FIGURE 1 | Illustration of the sequential steps in the synthesis ofTGF-βTGF-latent complex and secretion
Table 1 | AlteredTGF-β activity in knockout or mutant mice.
FIGURE 2 | Proposed model ofTGF-βreceptor binding site is induced. Binding of active TGF-receptor type II leads to the phosphorylation and recruitment of TGF-signaling.complex and/or conformational change such as exposure of the TGF-receptor type I into a
Table 2 |Therapeutic target forTGF-β activation mechanism in vivo.

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