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Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data

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Figure

Fig 1. Two-state model of bursty gene expression. The distribution of gene expression in a population of cells is partially caused by bursts of geneexpression
Fig 2. Pipeline for the analysis of single cell gene expression data. This paper develops several new tools for single cell analysis
Fig 3. In silico validation of single cell analysis pipeline. In order to estimate the accuracy of the new tools developed in this paper, each tool wasevaluated against simulated datasets
Fig 4. Application of SABEC to hematopoietic stem cells and progenitor populations. SABEC was used to identifysubpopulations of cells in the Moignard et al
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