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Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes

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Academic year: 2019

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Figure

Figure 3.Mstn inhibitsC2C12 myoblasts transfected with either negative control AntagomiR (AntagomiR-neg) or miR-34a-specimyoblasts treated without (0 Fndc5 gene expression via a miR-34a-dependent mechanism
Figure 4.Loss ofexperiment was repeated independently, but the data given are from one representative experiment) normalized to U6 (expression
Figure 5.Mstn regulation ofand WAT (repeated independently, but the data given are from one representative experiment) normalized toFndc5replicates) normalized to U6 (WAT (O (ORO) staining of WT and Fndc5 expression and browning in white adipocytes is miR-
Figure 6.Mstn modulates post-transcriptional expression of Fndc5 via a miR-34a-dependent mechanism

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