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Infection of Common Marmosets with GB Virus B Chimeric Virus Encoding the Major Nonstructural Proteins NS2 to NS4A of Hepatitis C Virus

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Figure

TABLE 1 Groups of marmosets infected with the HCV NS2 to -4A/GBV-B chimera
FIG 1 Diagram of the HCV NS2 to -4A chimeric genome. The HCV NS2 to -4A cDNA segment was integrated into the GBV-B cDNA genome (pGBB) bysubstituting the corresponding genes of GBV-B between EcoRI and SmiI restriction sites.
FIG 2 Detection of HCV NS2 to -4A chimera viremia in infected marmosets. (A) Correlation of viral loads tested with two sets of quantitative assays for GBV-B andobserved between the periods of FK506 administration and discontinuation in the course of infec
FIG 3 FISH detection of HCV NS2 to -4A chimeric RNA in hepatocytes ofliver tissues from infected marmosets
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