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Monoclonal Antibody-Based Antigenic Mapping of Norovirus GII.4-2002

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Academic year: 2019

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Figure

TABLE 1 MAbs developed in this study
FIG 1 EIA cross-reactivity of anti-GII.4-2002 MAbs to NoV VLPs. Purified MAbs were assayed by EIA for reactivity to GI and GII NoV VLPs
FIG 2 Characterization of PGM HBGA expression and VLP binding. (A) The HBGA phenotype of commercial PGM was determined by reactivity to a panel ofanti-HBGA MAbs by EIA
FIG 4 Heterotypic blockade of GII.4 VLP-Bi-HBGA interactions by anti-GII.4-2002-G6. (A) Increasing concentrations of anti-GII.4-2002-G6 anti-body were incubated with additional GII.4 VLPs positive for EIA reactivity andGI.1-1968 as a negative control
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