Antiviral effects of a thiol protease inhibitor on foot-and-mouth disease virus.

A further indication of the short-lived nature of the ASCs induced following vaccination with inactivated FMDV antigen is the very low number or absence of FMDV-specific ASCs detected

A strong FMDV- specific antibody response was detected in all infected cattle at 6 dpi: FMDV-ASC represented up to 0.39% of the total mononu- clear cells extracted from mandibular

Here we selectively amplify and analyze low-melting-temperature cDNA duplexes copied from FMDV genome populations passaged in the absence or presence of ribovirin Hypermutated

In this study it is demonstrated that the FMDV 3C protease, in addition to the FMDV Lb protease, induces the cleavage of the translation initiation factor eIF4G and furthermore

Since ARB did not inhibit translation, we can rule out inhibition of de novo protein synthesis as the mechanism of action for ARB suppression of resumption of FMDV replication

Since ARB did not inhibit translation, we can rule out inhibition of de novo protein synthesis as the mechanism of action for ARB suppression of resumption of FMDV replication

The fluorescence anisotropy assays were used to probe the substrate binding specificity of FMDV 3C pro using both unlabelled and fluorescein-labelled peptide substrates.. It was

Here we selectively amplify and analyze low-melting-temperature cDNA duplexes copied from FMDV genome populations passaged in the absence or presence of ribovirin Hypermutated