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The role of the histone variant H2A Z in early Xenopus laevis development

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Figure 1 Nucleosome core particle. A) Octomer of histone proteins (yellow, H2A; red, H2B; blue, H3; green, H4) with 147bp of DNA (phosphodiester backbones in dark green and brown), view from above the DNA superhelix
Figure 2 Chromatin foldingfibres are observed at interphase, these can be further compacted into fibres of around 700nm diameter and finally fully condensed mitotic chromosomes occur during mitosis and meiosis
Figure 3 Models of the 30nm Chromatin FibreRhodes and colleagues, the fibre is an interdigitated one-start helix (Robinson and Rhodes, 2006)
Table 2: Post translational modifications to canonical histones. For each modification the canonical histones modified (and amino acid numbers) are given as well as examples of functions and/or genomic locations affected
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Discussion Marker genes for mesoderm H2A.Z and developmental processes Conclusion

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