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Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation

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Figure

FIG 1 Chemical structures of BI-D and BIB-2.
FIG 2 Inhibition of virion maturation underlies ALLINI potency. (A) (Left) Quantitation of core morphotype frequencies (averageexperiments) for sets of 100 counted HIV-Luc particles; (right) representative TEM images of mature, eccentric, and immature viri
FIG 4 Examples of relatively rare morphotypes observed in populations ofWT virions. (A) Central tomographic slice of a WT particle without a core oreccentric condensate; (B) central tomographic slice (left) and correspondingtomo-bubblegram slice (right) of
FIG 5 Tomo-bubblegrams of HIV-1 particles. (A to X) Each pair of panels shows a central section from an initial tomogram (left) and the corresponding section fromthe tomo-bubblegram (right)
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