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Structure-function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids

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Figure

Figure 1.1 A simplified view of a chemical synapse. Both presynaptic and postsynaptic ligand gated ion channels are shown in green and the voltage gated calcium channels are shown in brown
Fig 1.2 Topology and diversity of nAChR subtypes. A: Topology of one subunit of nAChR
Figure 1.3 Unnatural amino acid incorporation by nonsense suppression (adapted from [55])
Fig 1.4 Expression system mostly used in our lab for structure-function studies of ion channels
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