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Phase 1b/2a study of trastuzumab emtansine (T DM1), paclitaxel, and pertuzumab in HER2 positive metastatic breast cancer

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Figure

Fig. 1 Design of (a) phase 1b and (b) phase 2a. aMTD is the highest dose at which 0/3 patients or 1/6 patients experienced a dose-limitingtoxicity
Table 1 Demographic and baseline characteristics
Table 2 All-grade AEs (occurring in ≥20 %) or grade 3–4 AEsa (occurring in >3 %) in phase 2a
Table 3 Efficacy

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