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cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin.

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Figure

Fig. 2. An originless vector backbone (KS) was unable to rep-licate significantly in the presence of E1 and E2 expressionvectors in the transient replication assay (3% of WT levels;
FIG. 3. In vivo transient replication of consecutive linker substitution mutants of the HPV-11 URR (nt 7871 to 95)
FIG. 4. Replication competence of double mutants 2�Materials and Methods). Arrows depict bands which represent replicated WT ormutant origin DNAs
FIG. 5. Summary of transient replication assay data for consecutive linker substitution mutants of the HPV-11 origin in the absence (A) or presence (B) of thecompetitor origin

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