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Abelson Phosphorylation of CLASP2 Modulates its Association With Microtubules and Actin

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Figure

Fig. 1. CLASP2 is tyrosine-phosphorylated by Abl kinase.GFP-CLASP2HEK293T cells following starvation and serum treatment for 30min in the presence or absence of STI-571 (1awasimmunoprecipitatedfromtransfected mM), a specificAbl inhibitor
Fig. 2. CLASP2 phosphorylation and interaction with Abl are enhanced by PDGF treatment
Fig. 3. Phosphorylation of CLASP2ctration dependence by normalized pixel intensity shows a sig-moidalphosphorylation
Fig. 4. Identification of CLASP2 tyrosine phosphorylation sites. A: Schematic representation of human CLASP2 constructs andvitro phosphorylation in Cos-7 cells (see B) and the region between the SacI and BamHI restriction sites was identified to be neces-s
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