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Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins

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Figure

FIG. 1. Model of the E2-dependent transcriptional activation func-tion. Brd4 links E2 to the active P-TEFb complex
FIG. 2. Brd4 mediates E2-dependent transcriptional activation ofthe authentic BPV1 LCR
FIG. 3. The transcriptional repression function of HPV16 E2 isindependent of Brd4. (A) Schematic of the E2-dependent transcrip-
FIG. 5. Repression of HPV18 transcription and stabilization of p53protein levels by HPV16 E2 in HeLa cells are not rescued by Brd4
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