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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Activates the JNK Pathway through Its Extreme C Terminus via a Mechanism Involving TRADD and TRAF2

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Figure

FIG. 1. The last 8 aa of LMP1 are critical for JNK and NF-B signalling. (A)vector HA-p46SAPKnoprecipitated from 250assays were performed as described in Materials and Methods
FIG. 4. Involvement of TRAF2 in LMP1-mediated JNK activation. (A) The effects of dominant-negative N-terminally deleted TRAF2 [TRAF2�CD40-mediated JNK activation
FIG. 4—Continued.
FIG. 6. NIK is a component of LMP1-mediated NF-�B but not JNK signal-ling. (A) Transfection of kinase-inactive NIK [NIK(KK429-430AA)] blocks

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