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Hepatitis C Virus Internal Ribosome Entry Site (IRES) Stem Loop IIId Contains a Phylogenetically Conserved GGG Triplet Essential for Translation and IRES Folding

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FIG. 2. Morpholino antisense inhibition of the HCV IRES. (A) Equal con-centrations (200 nM) of various antisense oligonucleotides (see Fig
FIG. 3. Mutational analysis of the HCV IRES IIId apical loop. (A) Specific IIId apical loop mutations and secondary structures
FIG. 4. Mapping of IIId nucleotides essential for IRES translation. (A and C) Specific IIId apical loop mutations and secondary structures
FIG. 6. Chimeric substitutions and effects on relative IRES translation. (A) Specific IIId apical loop mutations and secondary structures
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