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Polyfunctional anti human epidermal growth factor receptor 3 (anti HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers

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Academic year: 2020

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Figure

Fig. 1 Human epidermal growth factor receptor 3 (HER3)-specific antibody responses are induced by adenovirus encoding full length humanHER3 (Ad-HER3) in vivo
Fig. 2 Vaccine-induced antibody (VIA) in serum from mice immunized with adenovirus encoding full length human epidermal growth factor7.5:1) were tested
Fig. 3 Vaccine-induced antibody (VIA) in serum from mice immunized with adenovirus encoding full length human 3 epidermal growth factoranti-EGFR antibody (cetuximab, 401:100 HER3-VIA or GFP-VIA at 37 °C for 3 h
Fig. 4 In vivo effects of human epidermal growth factor receptor 3 (HER3) vaccine-induced antibody (HER3-VIA) on BT474M1 human breastdbreast cancers: *tumor xenografts
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