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Coreceptor Tropism Can Be Influenced by Amino Acid Substitutions in the gp41 Transmembrane Subunit of Human Immunodeficiency Virus Type 1 Envelope Protein

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Figure

TABLE 1. Coreceptor tropism and V3 sequences of env clones
FIG. 1. X4-tropic and dual-X clones are genetically distinct fromR5-tropic and dual-R clones
TABLE 2. Comparison of amino acid differences of selected env clones with different coreceptor tropism (V3 excluded)
FIG. 3. Chimeric envas measured by luciferase production (in RLU) on U87/CD4 target cells expressing CCR5 (gray bars) or CXCR4 (black bars)
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