• No results found

Within-Host Whole-Genome Deep Sequencing and Diversity Analysis of Human Respiratory Syncytial Virus Infection Reveals Dynamics of Genomic Diversity in the Absence and Presence of Immune Pressure

N/A
N/A
Protected

Academic year: 2019

Share "Within-Host Whole-Genome Deep Sequencing and Diversity Analysis of Human Respiratory Syncytial Virus Infection Reveals Dynamics of Genomic Diversity in the Absence and Presence of Immune Pressure"

Copied!
8
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

TABLE 1 Sequencing/assembly metrics for Illumina sequencing of longitudinal RSV-A samples
FIG 1 Plot of average diversity across the genome and lines reflecting the linear regression model coefficients; the R2 value refers to the overall fit of the model.Note that day �12 is the transition point, as it is the date of rise in absolute lymphocyte co
FIG 2 Variable amino acids in the RSV samples. Each sample date is represented by one row
FIG 3 Comparison of within-host and population-level G protein diversity. Black lines indicate the Shannon diversity index at each residue in the population-wide analysis, and dashed red lines indicate the maximum Shannon diversity index across all time po

References

Related documents

Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV

respiratory syncytial virus nonstructural protein 2 residues essential for exploitation of the host ubiquitin system and inhibition of innate immune responses.. Lyles, Wake

The rapid evolution of influenza virus under immune pressure is likely enhanced by the virus’s genetic diversity within a host, although antigenic change has rarely been investigated

Inability to evoke a long-lasting protective immune response to respiratory syncytial virus infection in mice correlates with ineffective nasal antibody responses. Asahi Y,

Actin and clathrin dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus RESEARCH Open Access Actin and

Dose selection for an adjuvanted respiratory syncytial virus F protein vaccine for older adults based on humoral and cellular immune responses.. Edwards, Vanderbilt University

The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA viral infections, including respiratory syncytial virus (RSV).. We previously reported that

To evaluate the efficacy of high titer respiratory syncytial virus (RSV) immune globu- lin (RSVIG) in the treatment of previously healthy children hospitalized with proven RSV