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Monocytes Treated with Human Immunodeficiency Virus Tat Kill Uninfected CD4+ Cells by a Tumor Necrosis Factor-Related Apoptosis-Induced Ligand-Mediated Mechanism

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Academic year: 2019

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Figure

FIG. 1. HIV Tat enters Jurkat cells but not U937 cells or monocytes. Jurkat cells, U937 cells, and monocytes were exposed to HIV Tat (100ng/ml) for 0 min (lanes 1, 5, and 10), 30 min (lanes 2, 6, and 11), 1 h (lanes 3, 7, and 12), or 3 h (lanes 4, 8, and 1
FIG. 4. HIV Tat only slightly increases membrane-associatedTRAIL expression in U937 cells and monocytes
FIG. 6. (A and B) Tat induces cytotoxic activity in monocytes.Human monocytes (effectors) were stimulated with 100 ng of Tat/ml

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