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pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence.

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Figure

FIG. 1. Amino acids deleted by MT mutants. MT is represented schemati-cally at the top, and the regions deleted from MT mutants are indicated under-
FIG. 2. The focus-inducing properties of MT deletion mutants. Ten micrograms of an MT cDNA-containing plasmid was transfected into Rat2 cells
FIG. 3. In vitro kinase assay of mutant MT polypeptides from G418-selectedcell lines. Lysates were prepared from cell lines expressing each MT deletion
FIG. 5. Phase-contrast photomicrographs of Rat2 cell lines expressing selected mutants of MT
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