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BRAF- and MEK-targeted small molecule inhibitors exert enhanced antimelanoma effects in combination with oncolytic reovirus through ER stress

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Figure

Figure 1 RT3D, PLX4720, and PD184352 are selective for melanoma relative to normal skin fibroblasts
Figure 2 Combining RT3D with BRAF and/or MEK inhibition enhances cell kill in melanoma cell lines
Figure S4).replication in the presence of PLX4720 or PD184352 by one-step
Figure 4 Enhanced apoptosis observed with RT3D and BRAF/MEK inhibition is mediated by ER stress
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