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Three-Dimensional Structure Determines the Pattern of CD4+ T-Cell Epitope Dominance in Influenza Virus Hemagglutinin

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Figure

FIG. 1. Similar profiles of CD4�virus HA in mice and humans infected with H3 or H1 strains of virus.(a) Schematic diagram of HA subdomains
FIG. 2. Structural context of structurally stable segments and re-gions of conserved epitope dominance in the HA precursor and the
FIG. 3. Influenza virus HA epitopes cluster on the flanks of struc-turally stable HA segments
FIG. 5. General model for HA processing and presentation that accounts for CD4�antigen segments
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