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A Lethal Disease Model for Hantavirus Pulmonary Syndrome in Immunosuppressed Syrian Hamsters Infected with Sin Nombre Virus

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Academic year: 2019

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Figure

TABLE 1 Dexamethasone and cyclophosphamide dosing schedulesa
FIG 2 Dexamethasone/cyclophosphamide immunosuppression allows SNV to be uniformly lethal in hamsters
FIG 3 Immunosuppression of SNV-infected hamsters allows viremia to be detected. Serum and lung isolated from dexamethasone-, cyclophosphamide-, and0.05; **,dexamethasone/cyclophosphamide-treated, SNV-infected hamsters on day 10 postinfection were evaluated
FIG 4 Dexamethasone/cyclophosphamide immunosuppression of SNV-infected hamsters creates lung pathology similar to that of ANDV-infected hamsters.H&E staining of lungs collected on day 10 from hamsters infected with SNV and treated with dexamethasone (A), c
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