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Connexin32 plays a crucial role in ROS mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion induced acute kidney injury

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Figure

Fig. 1 I/R-induced renal damage and renal tubular epithelial cells apoptosis were coincident with ERS activation
Fig. 3 TUDCA and 4-PBA pretreatment attenuated I/R-induced renal tubular epithelial cells apoptosis and renal damage
Fig. 4 NAC pretreatment diminished ROS production, ERS-related proteins expression and apoptosis or damage
Fig. 5 Cx32 gene deletion mitigated I/R-induced ROS generation and ERS activation. Changes of GRP78, XBP1and CHOP expressions were determined by western blotting analysis
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