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Human Dendritic Cells Transduced with Herpes Simplex Virus Amplicons Encoding Human Immunodeficiency Virus Type 1 (HIV-1) gp120 Elicit Adaptive Immune Responses from Human Cells Engrafted into NOD/SCID Mice and Confer Partial Protection against HIV-1 Chal

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FIG. 1. Vaccine scheme and analysis of human immune engraft-ment in hu-PBL-NOD/SCID mice
FIG. 2. Flow cytometric analysis of DC after amplicon transduction. DC transduced in vitro with HSV gp120abundant surface expression of gp120 as detected by flow cytometry with gp120-specific Ab
FIG. 3. Humoral immune responses in immunized hu-PBL-NOD/SCID mice. (A) Western blot analysis for HIV-1 gp120 Abs
FIG. 4. Cellular immune responses in hu-PBL-NOD/SCID mice.Mice were immunized with HSV-transduced DC; 7 days later, the
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