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Prion Interference Is Due to a Reduction in Strain-Specific PrPSc Levels

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Figure

TABLE 1. Clinical signs of and incubation periods for hamsters inoculated in the sciatic nerve with the DY TME agent prior tosuperinfection of hamsters with the HY TME agent
FIG. 3. Detection and differentiation of HY TME and DY TME PrPSc21-kDa nonglycosylated PrPR30 antibody can detect levels of HY TME PrPresults in DY TME PrP(lane 5) but not from HY TME PrPpresent on both HY TME and DY TME PrP by Western blot analysis
FIG. 6. Initial deposition of HY TME and DY TME PrPScpostinfection, indicating DY TME PrPipsilateral to mock inoculation of uninfected brain homogenate
TABLE 2. Clinical signs of and incubation periods for hamsters inoculated in the right sciatic nerve with the DY TME agent prior tosuperinfection in the left sciatic nerve with the HY TME agent
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