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Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.

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Figure

FIG.1.uniqueJ289quencestheoftheEBNA-LPofEBNA2BYRF1subfragmentstrain the the Schematic representation of the B95.8 EBV DNA se- present in the recombinant vectors J144 and J289
FIG. 2.cellpositive)JijoyeP3HR1B95.8ableLMPEBNA2A/BalentEBNA2BmajorproteinsCS.1-4 Immunoblot of protein extracts from EBV-negative BL- lines (BL40, BL2, BL30, and BL41) and their correspondingandB95.8convertsprobedwith MAbsspecificfor (PE2) and LMP (CS.1-4
Fig. 3BAlltransfectants shows an immunoblot of the same panel of BL30/P3 now probed with the anti-LMP MAb CS.1-4
Figure 6fectionsobserved also illustrates the pattern of protein expression in clones obtained from a parallel series of trans- involving the same target cells but using the LMP
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