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The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine

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Figure

TABLE 1. Oligonucleotides used for construction of pBIC, pCSIC, and chimeric p 138, p319.1, and p312.1 infectious clonesa
FIG. 1. (A) Construction of CSFV infectious cDNA clones pBICsites and nucleotide numbers are depicted (Primary macrophage cell cultures were infected (MOIvirus detected by immunohistochemistry as described in Material and Methods
FIG. 2. Construction of CSVF chimeric viruses. Corresponding restriction sites and nucleotide numbers are depicted.
TABLE 2. Swine survival, clinical scores, and fever responsefollowing infection with BICv, CSICv, and chimeric viruses
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