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Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells

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Academic year: 2019

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Figure

Figure 1. Proinflammatory cytokine and glucocorticoid regulation of 11promoter level.The combination of IL-1(RACE) analysis
Figure 2. Effect of NF-�B inhibitors on 11�-hydroxysteroid dehydrogenase type 1 (11�-HSD1) oxoreductase expression and activity in C2C12myoblasts
Figure 3. NF-�B is the major mediator of the induction of 11�-HSD1 by TNF� in fibroblasts (normal synovial and dermal; n � 3 independentpatient lines), osteoblasts, and myoblasts
Figure 5. Molecular analysis of the role of p38 MAPK signaling indual-specificity phosphatase 1 (DUSP-1) deletion in mouse embryonicfibroblasts (lines from 4 embryos)
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