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Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

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Figure

FIG 1 Inhibition of HIV-1 replication by IFN-� subtypes in vitro. (A and B) The infectivity of supernatants harvested from PBMCs exposed to X4-tropicHIV-1NL4-3_IRES_eGFP in the presence of different human IFN-� subtypes for 2 days was determined
FIG 2 IFN-administered daily for 10 consecutive days, followed by sample collection ei-ther 24 h after the final injection (11 dpi) or after an additional 10-day periodof no treatment (21 dpi)
FIG 3 Cessation of IFN-standard deviations [SD]) in plasma of mice 24 h after the final IFN injection(11 dpi) and after 10 additional days of no treatment (21 dpi)
FIG 5 Plasma cytokine analysis. (A) Plasma was collected 24 h after the finalIFN-assayed for human cytokine and chemokine levels using a custom 11-plex beadassay
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