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The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication

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Figure

FIG 1 The MNV NS3 protein associates with the viral replication complex. Thawed cryosections of MNV-infected RAW264.7 cells were fixed at 12 h p.i
FIG 2 The MNV NS3 protein associates with dsRNA within the viral replication complex. Thawed cryosections of MNV-infected RAW264.7 cells fixed at 12 h p.i.(A and B) and 18 h p.i
FIG 3 Comparative analysis of the Norwalk virus and murine norovirus NS3 proteins. (A) ClustalW alignment of the amino acid sequences of NV NS3corresponding to conserved amino acids
FIG 4 Both MNV NS3 and NV NS3 show a vesicular pattern upon transfection. Vero cells were transfectedwith either MNV NS3- or NV NS3-containing plasmids and fixed at 24 h p.t., and their localization wasassessed by IF analysis
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