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Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

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Academic year: 2019

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Figure

Figure 1. Protective effect of carnosine against brain damage during ischemic strokeIschemic stroke was achieved by middle cerebral artery occlusion (MCAO) in rats
Figure 2. Inhibitory effect of carnosine on autophagy in ischemic brainBrain homogenates were isolated from contralateral (Contra) or ipsilateral (Ipsi) hemispheres from saline- or carnosine (1000 mg/kg; 6 hr post treatment)-administered rats following pMC
Figure 3. Protective effect of carnosine on mitochondrial damage in ischemic brainBrain mitochondria were isolated from contralateral (Contra) or ipsilateral (Ipsi)
Figure 4. Inhibitory effect of carnosine on neuronal autophagy following NMDA stimulationPrimary cortical neurons were pre-treated with carnosine 30 min prior to exposure to

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