Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system.

We constructed a single-point mutant of OM carrying a G at nt 926, Mah-VP4V62, as described in Materials and Methods, and the mouse neurovirulence was compared with that of the

Studies by the environmental protection agency, as well as other international regulatory agencies, have shown that chronic low level exposure to lead is associated with

To further evaluate the permissivity of murine lymphocytes for MV in vitro, the rates of MV production in different CD46- expressing murine cell types was compared with those of

After the infection period, the cells were washed, external virus was inactivated by low-pH treatment, new medium without inhibitors was added, and the cells were harvested 24 h

The nucleotide and deduced amino acid sequences of the 15 BDV ORF-II cDNA clones from the PBMC of three psychiatric patients were compared.. For this comparison, all amino acid

In contrast to the IE promoters, the gC promoter of the late gene class did not support long-term expression of b -galactosidase; instead, b -galactosidase was detected in only a

Virus was not recovered from substitutions which blocked or substantially reduced cleavage in the cell-free assay, suggesting that efficient cleavage at the 2B/3 site is required

To determine whether the depen- dence of virus late functions on the amino terminus occurs in other cell types, we assayed viral DNA replication in two nontransformed fibroblast