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Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression

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Academic year: 2019

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Figure

FIG. 1. Analysis of the activation status of the IRE1/XBP-1 andATF6 pathways during MHV infection
FIG. 3. Northern blot analysis of UPR target genes during MHVinfection. DBT cells were infected with MHV or treated with tunica-
FIG. 4. Analysis of XBP-1 and ATF6�RNA was extracted and subjected to Northern blot analysis usingprobes against XBP-1 or ATF6fection
FIG. 6. Analysis of the eIF2�(A) Lysates were generated from either MHV-infected cells or cellstreated with tunicamycin (Tun) (2was performed using antibodies directed against phosphorylatedeIF2thionine for 15 min
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