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Central Nervous System Pathology Caused by Autoreactive CD8+ T-Cell Clones following Virus Infection

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Figure

FIG. 2. All three TMEV-induced CD8�1C, and 8b-1C, proliferated in response to TMEV-infected APCs (*,�clones proliferated less well to uninfected syngeneic APCs
FIG. 3. TMEV-induced CD8�MHC class I or II antibody. MHC class I antibody inhibited the killing of PSJL cells (left), while MHC class II antibody showed no significantuninfected syngeneic PSJL cells were used as target cells
FIG. 4. CNS degeneration caused by intracerebral adoptive transfer of TMEV-induced T-cell clones

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