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The Zinc Finger Antiviral Protein Directly Binds to Specific Viral mRNAs through the CCCH Zinc Finger Motifs

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Figure

FIG. 3. ZAP does not target AREs. pGL3-Luc reporters contain-ing different types of AREs were cotransfected into 293A cells with an
FIG. 4. Analysis of the effect of each zinc finger mutation on thefunction of ZAP. Each zinc finger of NZAP-Zeo was disrupted by the
FIG. 5. In vitro binding of ZAP to target RNA. The lysates ofZAP-expressing or control cells were mixed with 9E10 anti-Myc anti-

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