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The cellular transcription factor E2f requires viral E1A and E4 gene products for increased DNA-binding activity and functions to stimulate adenovirus E2A gene expression.

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Figure

FIG.1.clonedacrylamidethethelabeled Early viral gene expression in In340 virus-transformed CREF cell lines
FIG. 3.andandvirus,clearindicated.hDNA-bindingindicatednosequences, in exolll protection assay for the binding of E2f to DNA using extracts derived from virus-infected CREF cells transformed CREF cell lines
TABLE 1. Quantitation of viral early cytoplasmic mRNAlevels and cellular E2f DNA-binding levels in adenovirus-transformed CREF cell linesa
FIG. 5.formedtransformedsequences,dayseitherexoIll(numbersonlegendcellno exollI protection assay for the binding of E2f to E2A using extracts derived froman AdShrlvirus-trans- CREF cell line

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