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Effectiveness of two different dose administration regimens of an IL 15 superagonist complex (ALT 803) in an orthotopic bladder cancer mouse model

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Figure

Fig. 1 Study treatment schema. Treatment with PBS (negative control), BCG (positive control), intravesical (IVe) ALT-803, SQ ALT-803, IVe BCG + IVe ALT-803 and IVe BCG + SQ ALT-803 commenced on week 13 after 12 week exposure to 0.05% N-butyl-N-(4-hydroxybu
Fig. 2 Anti-tumor activity of BCG, ALT-803 and ALT-803 plus BCG. a On week 20, mice were sacrificed and resected bladders were fixed in 10% buffered formalin and embedded in paraffin and subsequently stained with H&E
Fig. 3 Treatment-related infiltration of lymphocytes in bladders of female mice bearing tumors

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