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Establishment of a patient derived orthotopic osteosarcoma mouse model

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Figure

Figure 1 Representative MRI and μCT images of mouse xenografts 4 to 8 weeks after intratibial transplantation of patient-derived human OStissue showing tibial tumor mass
Figure 2 Representative MRI images of T1 weighed (T1w) and T2 weighed (T2w) performed at week 4
Figure 3 Establishment of patient-derived mouse model. Human OS tissue was transplanted into 6 mice with success rates of 50% in passage 1(P1), 66% in passage 2 (P2) and 100% in passage 3 (P3)
Figure 4 Establishment of the primary tumor cell line OS-RH-2011/5. The original tumor tissue was collected and directly cultivated into medium(P1*)
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