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Template Switches during Plus-Strand DNA Synthesis of Duck Hepatitis B Virus Are Influenced by the Base Composition of the Minus-Strand Terminal Redundancy

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Figure

FIG. 1. Model for transcription and replication of DHBV. (A) cccDNA or in vitro-synthesized circular DNA monomer (gray circle) serves asthe transcriptional template for synthesis of the terminally redundant pgRNA (black line)
FIG. 2. For most variants, the predominant 5�intermediates isolated from LMH cells using primer 3 to detect the 5 terminus of minus-strand DNA is at coordinate 2537
FIG. 4. Primer extension assays. (A) Primer extension assay used tomeasure circularization efficiency
TABLE 1. Replication measurements for each r varianta

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