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Evasion of the Mucosal Innate Immune System by Herpes Simplex Virus Type 2

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Figure

FIG. 1. Significant presence of HSV-2 DNA and expression of HSV-2 RNA and antigens in lesion biopsy specimens from individuals withrecurrent mucocutaneous HSV-2 infection
FIG. 2. Transcriptional profiling of skin biopsy specimens at lesion and posthealing stages
FIG. 3. Human skin biopsy specimens taken from acute HSV-2 lesions show little type I IFN expression but strong IFN-�(A) Expression of type I IFN (indicated as IFN-biopsy specimens relative to that in their matched control biopsy specimens in arrays
FIG. 4. Expression patterns of ISGs in acute lesion biopsy specimens. (A) Expression patterns of ISGs that showed twofold or greater increasesin expression in any of the four acute lesion biopsy specimens relative to that in their matched controls in trans
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