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Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients

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Academic year: 2019

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Figure

Table 1. Previous studies assessing clonal evolution in myeloma.
Figure 1. The mutational profile at presentation and relapse. (A) Recurrent mutations in myeloma and mutations within the genes associated with immunomodu-latory agent action
Figure 2. The proportion of patients with a change in the profile of mutations known to be recurrent in myeloma or important in immunomodulatory mechanismof action at relapse.The proportion of observation patients (n=26) with a change in the profile of rec
Figure 3. Number of mutational clus-ters at presentation and relapse. (A)
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